SELECTED IMPORTANT SAFETY INFORMATION

Some people who have taken medicine like ATRIPLA have developed build up of lactic acid in the blood, which can be a serious medical emergency that can lead to death.
Some people who have taken medicines like ATRIPLA have developed
serious liver problems, with liver enlargement and fat in the liver, which can lead to death.
If you also have hepatitis B virus (HBV) infection and you stop taking ATRIPLA, your hepatitis may suddenly
get worse. ATRIPLA is not approved for the treatment of HBV.

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information for healthcare professionals

Please click here for more information about these warnings, including signs and symptoms, and other Important Safety Information.

How Does ATRIPLA Work?

ATRIPLA contains three HIV medicines in one pill: SUSTIVA^® (efavirenz), EMTRIVA^® (emtricitabine) and VIREAD^® (tenofovir disoproxil fumarate). This combination works to help lower the amount of HIV in the blood (called viral load) by interfering with the way HIV makes copies of itself (called viral replication). Lowering the amount of HIV in the blood may also help increase the number of T-cells (also called CD4+ cells). CD4+ cells are an important part of your immune system because they help the body fight infections.

For many patients, ATRIPLA may be a complete regimen, with three medicines from two different "classes," or types of drug, in one pill. For some patients, ATRIPLA may be taken with other medicines to treat HIV-1. ATRIPLA contains two NRTIs (emtricitabine and tenofovir disoproxil fumarate) and one NNRTI (efavirenz). Regimens that combine HIV medicines from different classes are effective because they help to slow HIV multiplication during several stages of the process.

ATRIPLA does not cure HIV-1 infection or AIDS and you may continue to experience illnesses associated with HIV-1 infection, including opportunistic infections.

See your healthcare provider regularly while taking ATRIPLA.

Please click here for Important Safety Information, including information on buildup of lactic acid in the blood, serious liver problems, and sudden worsening of hepatitis B virus.

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(c) 2012 Bristol-Myers Squibb Company.

ATRIPLA and ATRIPLA Peer Advocate Network are registered trademarks of Bristol-Myers Squibb & Gilead Sciences, LLC. SUSTIVA is a registered trademark of Bristol-Myers Squibb Company. COMPLERA, EMTRIVA, GILEAD, GSI, HEPSERA, TRUVADA, and VIREAD are trademarks of Gilead Sciences, Inc., or its related companies. All other trademarks referenced herein are the property of their respective owners.

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