SELECTED IMPORTANT SAFETY INFORMATION
Some people who have taken medicine like ATRIPLA have developed
the following:
  • A serious condition called lactic acidosis (buildup of an acid in the blood)
  • Serious liver problems called hepatotoxicity
  • A "flare-up" of hepatitis. If you have HIV-1 and hepatitis B virus (HBV) infection and you stop taking ATRIPLA, you may get a "flare-up" (a sudden worsening) of your hepatitis
Please click here for additional Important Safety Information, including Boxed WARNINGS.
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Important Safety Information

Treatment Options for HIV

Talk to a doctor as soon as you find out that you are HIV positive. Your doctor will give you a thorough examination, including laboratory tests to determine whether you need to start HIV treatment or not. It is important to discuss your medical history, lifestyle, and special concerns in an honest way to make sure you and your healthcare provider determine the treatment option that's best for you.

Types of treatment for HIV

While there is no cure for HIV, there are many different combinations of medicines available to treat HIV. It's different for each person. Your doctor will look at your physical exam, laboratory results, treatment history and individual needs to prescribe the best treatment for you.

Antiretroviral drugs are used to help control HIV. These drugs attack HIV and help keep it from spreading in your body. There are six different classes of HIV drugs. Each drug class fights HIV in a different way. The primary difference between each class is the stage of HIV replication (when the virus makes copies of itself) that the drugs target.

Classes of HIV drugs

NRTIs are fake building blocks that stall HIV from making copies of itself.
NNRTIs bind to and disable a protein called reverse transcriptase that HIV needs to make more copies of itself.
PIs disable a protein called protease that HIV needs to make more copies of itself.
Entry inhibitors block HIV entry into T-cells.
Fusion inhibitors block HIV entry into T-cells.
Integrase inhibitors disable a protein called integrase that HIV uses to put its genes into the T-cells' genes.

What is HAART?

  • HAART stands for Highly Active Antiretroviral Therapy
  • HAART combines different kinds of drugs, so that they can help slow the copying of HIV
  • HAART means taking at least 3 drugs from at least 2 classes
The Department of Health and Human Services (DHHS) recommends a preferred regimen of
1 NNRTI or 1 PI (preferably boosted with ritonavir) or 1 INSTI and 2 NRTIs for patients new to treatment.

Examples of Haart regimens

There is often new information about HIV. Help yourself by learning everything you can about the different treatments. Talk to your doctor about what you learn and any questions you may have.

ATRIPLA does not cure HIV-1 and has not been shown to prevent passing HIV-1 to others.

Ask your doctor if ATRIPLA is right for you, and see your healthcare provider regularly. Individual results may vary.

Please click here for Important Safety Information, including information on lactic acidosis, serious liver problems, and flare-ups of hepatitis B virus (HBV).



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