SELECTED IMPORTANT SAFETY INFORMATION
  • Some people who have taken medicine like ATRIPLA have developed build up of lactic acid in the blood, which can be a serious medical emergency that can lead to death.
  • Some people who have taken medicines like ATRIPLA have developed

    serious liver problems, with liver enlargement and fat in the liver, which can lead to death.

  • If you also have hepatitis B virus (HBV) infection and you stop taking ATRIPLA, your hepatitis may suddenly
    get worse.
    ATRIPLA is not approved for the treatment of HBV.
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Important Safety Information

About ATRIPLA



ATRIPLA combines two nucleoside reverse transcriptase inhibitors (NRTIs) and one
non-nucleoside reverse transcriptase inhibitor (NNRTI) in one pill.


The first HIV regimen in one pill daily. ATRIPLA may be taken alone or with other HIV medicines.

With the power of three HIV medicines in one pill, ATRIPLA offers an entire HIV regimen in a single daily dose, for many patients.

ATRIPLA is the #1 prescribed HIV regimen.*

  • ATRIPLA is the only 1 pill daily HIV regimen with 3 DHHS-preferred meds for patients new to therapy.
  • ATRIPLA is proven to lower viral load to undetectable and helps raise T-cell (CD4+) count to help control HIV through 3 years of a clinical study in patients new to therapy.
    • Through 3 years, 71% of patients taking the meds in ATRIPLA had undetectable viral loads versus 58% for
      COMBIVIR (lamivudine/zidovudine) + SUSTIVA
    • At Year 3, the average increase of CD4+ cell count was 312 cells/mm3 for patients taking the meds in ATRIPLA  versus 271 cells/mm3 for COMBIVIR + SUSTIVA
The long-term effects (beyond 3 years) of ATRIPLA are not known at this time. People taking ATRIPLA may still get opportunistic infections or other conditions that happen with HIV-1 infection.

ATRIPLA does not cure HIV-1 infection or AIDS and you may continue to experience illnesses associated with HIV-1 infection, including opportunistic infections.

MEDICINES YOU SHOULD NOT TAKE WITH ATRIPLA

  • Do not take ATRIPLA if you are taking the following medicines because serious and
    life-threatening side effects may occur when taken together: Vascor® (bepridil),
    Propulsid® (cisapride), Versed® (midazolam), Orap® (pimozide), Halcion® (triazolam), or ergot medications (for example, Wigraine® and Cafergot®).
  • ATRIPLA should not be taken with: Combivir® (lamivudine/zidovudine),
    COMPLERA® (emtricitabine/rilpivirine/tenofovir disoproxil fumarate),
    EMTRIVA® (emtricitabine), Epivir® or Epivir-HBV® (lamivudine),
    Epzicom® (abacavir sulfate/lamivudine), Trizivir® (abacavir sulfate/lamivudine/zidovudine), TRUVADA® (emtricitabine/tenofovir DF), or VIREAD® (tenofovir DF), because they contain the same or similar active ingredients as ATRIPLA. ATRIPLA should not be used with SUSTIVA® (efavirenz) unless recommended by your healthcare provider.
  • Vfend® (voriconazole) should not be taken with ATRIPLA since it may lose its effect or may increase the chance of having side effects from ATRIPLA.
  • Do not take St. John’s wort (Hypericum perforatum), or products containing St. John’s wort with ATRIPLA. Taking St. John’s wort may decrease ATRIPLA levels and lead to increased viral load, and possible resistance to ATRIPLA or cross-resistance to other
    anti-HIV-1 drugs.
  • ATRIPLA should not be used with HEPSERA® (adefovir dipivoxil).

These are not all the medicines that may cause problems if you take ATRIPLA. Tell your healthcare provider about all prescription and nonprescription medicines, vitamins, or herbal supplements you are taking or plan to take.

Ask your doctor if ATRIPLA is right for you, and see your healthcare provider regularly. Individual results may vary.

Please click here for Important Safety Information, including information on buildup of lactic acid in the blood, serious liver problems, and sudden worsening of hepatitis B virus.

Please click on each product's name to view Full Prescribing Information, including Boxed WARNINGS for ATRIPLA, TRUVADA, EMTRIVA, VIREAD, and Full Prescribing Information for SUSTIVA.

*Synovate Healthcare Data; US HIV Monitor, Q1, 2010.
The Department of Health and Human Services.
Undetectable was defined as a viral load of less than 400 copies/mL.
Patient Product Information
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(c) 2012 Bristol-Myers Squibb Company.

ATRIPLA and ATRIPLA Peer Advocate Network are registered trademarks of Bristol-Myers Squibb & Gilead Sciences, LLC. SUSTIVA is a registered trademark of Bristol-Myers Squibb Company. COMPLERA, EMTRIVA, GILEAD, GSI, HEPSERA, TRUVADA, and VIREAD are trademarks of Gilead Sciences, Inc., or its related companies. All other trademarks referenced herein are the property of their respective owners.

Patient models are used on this Web site. The information on this site is intended for residents of the United States who are 18 years of age or older. The content of this site is protected under applicable copyright and trademarks law.

This site may contain, from time to time, information related to various health, medical and fitness conditions, and their treatment. Such information is not meant to be a substitute for the advice provided by a physician or other medical professional. You should not use the information contained herein for diagnosing a health or fitness problem or disease. You should always consult a physician and/or a healthcare provider.

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